2VIW: Fragment-based Discovery Of Mexiletine Derivatives As Orally Bioavailable Inhibitors Of Urokinase-type Plasminogen Activator

PDB ID: 2VIWDownload
MMDB ID: 62023
PDB Deposition Date: 2007/12/5
Updated in MMDB: 2012/09
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 2VIW: monomeric; determined by author and by software (PQS)
Molecular Components in 2VIW
Label Count Molecule
Protein (1 molecule)
1
Urokinase-type Plasminogen Activator Chain B
(Gene symbol: PLAU)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
Acetate IonAcetate Ion
2
1
4-(2-Aminoethoxy)-N-(3-Chloro-2-Ethoxy-5-Piperidin-1-Ylphenyl)-3,5-Dimethylbenzamide4-(2-Aminoethoxy)-N-(3-Chloro-2-Ethoxy-5-Piperidin-1-Ylphenyl)-3,5-Dimethylbenzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303